Microvessel damage in acute respiratory distress syndrome: the answer may not be NO †
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Microvessel damage in acute respiratory distress syndrome: the answer may not be NO.
Acute lung injury and acute respiratory distress syndrome (ARDS) arise from a wide variety of causes, but the common clinical manifestations are refractory hypoxaemia and increased pulmonary vascular resistance. A major pathological feature of acute lung injury and ARDS is damage to the pulmonary vascular endothelium, secondary to the activation and adhesion of platelets, neutrophils and monocy...
متن کاملAcute respiratory distress syndrome.
The acute respiratory distress syndrome (ARDS) is a serious and complex clinical problem that often threatens the lives of patients. Emerging clinical data suggest that the survival of patients with this disorder may have improved during the last two decades, presumably because of advances in supportive medical care. Among the supportive therapies used to treat patients with ARDS, none is more ...
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ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) is a clinical condition characterized by impaired gas exchange as a result of the accumulation of edema in the alveolar space. The clinical management of ARDS patients includes mechanical ventilation with high oxygen concentrations. Mechanical ventilation alleviates the work of breathing and hypoxemia while allowing time for the lungs to recover from t...
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VALID AND RELIABLE DEFINItions are essential to conduct epidemiological studies successful ly and to facilitate enrollment of a consistent patient phenotype into clinical trials. Clinicians also need such definitions to implement the results of clinical trials, discuss prognosis with families, and plan resource allocation. Following the initial description of acute respiratory distress syndrome...
متن کاملAcute Respiratory Distress Syndrome
ACCP Critical Care Board Review 2003 T acute respiratory distress syndrome (ARDS) and the related acute lung injury (ALI) syndromes are forms of Type I or acute hypoxemic respiratory failure (AHRF). This form of lung dysfunction rises from diseases causing collapse and/or filling of alveoli with the result that a substantial fraction of mixed venous blood traverses nonventilated airspaces, effe...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 2001
ISSN: 0007-0912
DOI: 10.1093/bja/87.2.272